![]() ![]() Thus, the cure probabilities provided by the calculator should be viewed as a starting point for the provider’s own estimate of the patient’s cure probability. They also do not include updated information available to clinicians about the status of the patient’s cancer at a subsequent evaluation after diagnosis. ![]() The cure probabilities are based on average outcomes for similar patients in the SEER data, and they do not account for molecular tumor characteristics, which can have prognostic importance, or treatment details. The information used in the cure probability calculations includes the patient’s sex, age at diagnosis, cancer subsite (proximal colon, distal colon, rectum), cancer stage at diagnosis, and initial cancer treatment (surgery, radiation, chemotherapy). The cure probabilities provided by this calculator are based on statistical modeling of data on patients with colorectal cancer in the Surveillance, Epidemiology, and End Results (SEER) cancer registries. This approach corresponds to identifying patients who have a high likelihood of being cured of their cancer For patients with a history of cancer, such considerations indicate a need to systematically select those individuals for transplantation who have an acceptably low risk of cancer recurrence and death from their cancer. However, the decision regarding whether a patient can be safely placed on the organ transplant waitlist takes account of comorbid medical conditions that would make transplantation high-risk or of limited benefit to the patient. Solid organ transplantation can enable long-term survival for patients with end-stage organ disease. This calculator tool was developed for decision-making regarding when it is safe to offer solid organ transplantation. The cure probability increases with longer time since cancer diagnosis, as the patients who are destined to die from their cancer are removed from the population and those who remain alive have a better prognosis. For an individual patient, the cure probability is a measure of prognosis and ranges from 0 (people who are not cured from their cancer and will eventually die from their cancer) to 1 (people who are cured from their cancer and will never die from it), with intermediate values reflecting the likelihood that a person is in one or the other group. This probability may be useful for counseling patients and clinical decision-making.įor a population of cancer patients, the cure probability is the proportion of people who will not die from their cancer. This calculator was developed for use by health professionals to estimate the probability that a patient with colorectal cancer is cured of their cancer. ![]()
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